
Gabapentin is used for the management of neuropathic pain, epilepsy, etc. Its off-label application for anxiety disorders has received some attention over the years. As a modifier of nerve function, its use for anxiety symptom relief is interesting both to professionals and patients alike.This article examines the scientific basis, clinical observations, and considerations surrounding Gabapentin’s off-label application for anxiety. Mechanism of Action and Anxiety Relief The mechanism of action involves the enhancement of the brain’s inhibitory neurotransmission. Neurosis which can be antagonized may lead to cognitively excitable regions of the brain which possibly allows anxiety relief.